This research line focuses on the development and application of an innovative scientific approach: "Multi-Scale Integrated Analysis of Societal and Ecosystem Metabolism" (MuSIASEM). MuSIASEM integrates biophysical and socioeconomic variables across multiple scales, thus establishing a link between the metabolism of socio-economic systems and the potential constraints of the embedding natural environment. Integrated sets of indicators for the assessment of sustainability issues can be chosen "à la carte" by social actors in relation to multiple criteria of performance. Recent research has focused on the nexus between land use, food, energy and water in relation to sustainable development goals. Together with the research line of Louis Lemkow, 'Science and technology studies', we form the consolidated research group Integrated Assessment: Sociology, Technology and the Environment (IASTE). Key Words: Multi-criteria analysis of sustainability; Integrated assessment of scenarios and technological changes; Energy analysis; Biocomplexity and sustainability; Multi-scale integrated analysis of societal and ecosystem metabolism; Water-energy-food nexus; Science for governance.